Research

Research

Research

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Research fields

  • Hybrid materials for tissue regeneration
  • Biomimetic mineral formation
  • Bioresponsive materials and hybrid materials
  • Composite/hybrid materials for bone replacement
  • Sol-gel process under defined climatic conditions
  • Mechanical testing
  • Atomic force, electron and fluorescence microscopy
  • Cultivation of stem cells for tissue engineering
  • Bone remodelling, osteoblasts, osteoclasts
  • Bioreactors / flow chambers

DFG-Projekt (Nahost-Kooperationsprogramm)
Crustacean bifunctional proteins in mineralized exoskeleton – a model for biomimetic injectable bone substitutes

The focus of the project is on the production and selection of recombinant proteins and their use in chitin gels in the context of bone regeneration. We have focused on basic research into the influence of crustacean proteins on mineralization. Initial binding analyses and investigations of the mineralization-mediating properties in a special chamber are planned. The long-standing cooperation between BGU and TUD has already proven the added value of the interdisciplinary approach. In the future, these bifunctional proteins could be an innovative component of an injectable bone substitute.

Duration: 2024-2027

Principal investigator: - FSU Jena: Dr. Benjamin Kruppke

Principal investigator:  - Ben Gurion Universität (Israel): Prof. Amir Sagi

Project number: 538923079