Popp Group

Chair of Physical Chemistry II (Material and Biophotonic)

The research of the working group focuses mainly on the development and application of innovative Raman-based methods to answer biomedical questions. Raman spectroscopy and the various Raman-based technologies such as Raman microscopy, SERS or CARS are powerful tools for addressing a broad range of bioanalytical and biomedical problems such as the rapid identification of pathogens, the sensitive monitoring of low-concentration molecules (e.g. drugs or metabolites) or the objective clinical evaluation of cell and tissue samples for early cancer detection.

Contact

Jürgen Popp, Univ.-Prof. Dr
Chair of Physical Chemistry II
Prof. Dr. Jürgen Popp
Image: Sven Doering / Agentur Focus
Helmholtzweg 4
07743 Jena Google Maps site planExternal link

Staff

  1. Agyemang, Michael Freduah Chair of Physical Chemistry II (Material- and Biophotonics)
  2. Cui, Dongyu Chair of Physical Chemistry II (Material- and Biophotonics)
  3. Edwards, Akuila Lotesha Jamela L. Chair of Physical Chemistry II (Material- and Biophotonics)
  4. Elmashtoly, Samir Fathy Abdelmonem, Dr Chair of Physical Chemistry II (Material- and Biophotonics)

    Room 204
    Philosophenweg 7
    07743 Jena

  5. Enghardt, Marie-Luise Chair of Physical Chemistry II (Material- and Biophotonics)
  6. Frempong, Sandra Baaba Chair of Physical Chemistry II (Material- and Biophotonics)
  7. Girnus, Sophie Chair of Physical Chemistry II (Material- and Biophotonics)
  8. Grohs, Richard, Dr Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E007
    Helmholtzweg 4
    07743 Jena

  9. Jana, Sankar Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E007
    Helmholtzweg 4
    07743 Jena

  10. Luo, Ruihao Chair of Physical Chemistry II (Material- and Biophotonics)

    JenTower, Room 15S05
    Leutragraben 1
    07743 Jena

  11. Marasinghe Arachchige, Lakruvini Perera Chair of Physical Chemistry II (Material- and Biophotonics)
  12. Motganhalli Ravikumar, Ramya Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E006
    Helmholtzweg 4
    07743 Jena

  13. Naumann, Frida Chair of Physical Chemistry II (Material- and Biophotonics)
  14. Pistiki, Aikaterini Chair of Physical Chemistry II (Material- and Biophotonics)
  15. Popp, Jürgen, Univ.-Prof. Dr Chair of Physical Chemistry II (Material- and Biophotonics)
    Prof. Dr. Jürgen Popp
    Image: Sven Doering / Agentur Focus
  16. Ramoji, Anuradha, Dr Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E006
    Helmholtzweg 4
    07743 Jena

    Dr. Anuradha Ramoji
    Image: Dr. Anuradha Ramoji
  17. Rösch, Petra, Dr Chair of Physical Chemistry II (Material- and Biophotonics)
    Dr. Petra Rösch
    Image: Dr. Petra Rösch
  18. Salbreiter, Markus Chair of Physical Chemistry II (Material- and Biophotonics)
  19. Schmitt, Michael, apl. Prof. Dr Chair of Physical Chemistry II (Material- and Biophotonics)
    Prof. Dr. Michael Schmitt
    Image: Prof. Dr. Michael Schmitt
  20. Silge, Anja, Dr Chair of Physical Chemistry II (Material- and Biophotonics)

    Room 331
    Albert-Einstein-Straße 9
    07745 Jena

    Dr. Anja Silge
    Image: Dr. Anja Silge
  21. Spoerer, Jana Chair of Physical Chemistry II (Material- and Biophotonics)

    Abbe Center of Photonics
    Albert-Einstein-Straße 6
    07745 Jena

  22. Tarcea, Nicolae, Dr Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E007
    Helmholtzweg 4
    07743 Jena

    Dr. Nicolae Tarcea
    Image: Dr. Nicolae Tarcea
  23. Wagenhaus, Annette Chair of Physical Chemistry II (Material- and Biophotonics)

    Room E010
    Helmholtzweg 4
    07743 Jena

199 Publikationen filtern

Die Publikationen filtern

  3. Raman imaging of molecular groups in the wavenumber silent region

    Year of publicationPublished in:Analytical & bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry, Analusis and Quimica analitica C. Schultz, J. Popp
    Raman imaging in the wavenumber silent region emerged around 15 years ago as a powerful tool for visualizing biomolecules and synthetic compounds in complex environments with minimal spectral and biological interference. Since then, the field has advanced from simple proof-of-concept studies using available tags to the rational design of highly efficient Raman labels with sharp silent region signatures, now applied to real biological and biomedical questions. This review traces the evolution from the versatility of label-free Raman to the increasing relevance of labeled strategies, emphasizing how tag design influences functionality, application, and impact. We highlight recent progress in both the synthesis and deployment of tags tailored for specific cellular targets and processes and discuss the emerging need for labeled strategies to meet the demands of sensitivity, multiplexing, and biocompatibility in complex systems. Through this design-to-application perspective, the review provides a comprehensive overview of the current capabilities and significant applications, and identifies key future directions to fully exploit the potential of silent region Raman imaging.
    University Bibliography Jena:
    fsu_mods_00027001External link

  4. Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2025

    Year of publication
    University Bibliography Jena:
    fsu_mods_00026043External link

  7. Multiplex electrochemical aptasensor for the simultaneous detection of linomycin and neomycin antibiotics

    Year of publicationPublished in:Talanta: the international journal of pure and applied analytical chemistry W. Al borhani, A. Rhouati, D. Cialla-May, J. Popp, M. Zourob
    University Bibliography Jena:
    fsu_mods_00017367External link

  9. A multiplexing immunosensing platform for the simultaneous detection of snake and scorpion venoms: Towards a better management of antidote administration

    Year of publicationPublished in:Talanta: the international journal of pure and applied analytical chemistry A. AlMusharraf, A. Rhouati, D. Cialla-May, J. Popp, M. Zourob
    University Bibliography Jena:
    fsu_mods_00019172External link

  10. Development of a label-free, functional, molecular and structural imaging system combining optical coherence tomography and Raman spectroscopy for in vivo measurement of rat retina

    Year of publicationPublished in:Biomedical Optics Express R. Sentosa, M. Salas, C. Merkle, M. Eibl, W. de Jong, A. Amelink, M. Schmitt, I. Krestnikov, V. Shynkar, M. Kempe, T. Schmoll, B. Baumann, M. Andreana, A. Unterhuber, J. Popp, W. Drexler, R. Leitgeb
    In vivo access to molecular information of retinal tissue is considered to play a critical role in enabling early diagnosis of ophthalmic and neurodegenerative diseases. The current gold standard of retina imaging, optical coherence tomography and angiography provides only the retinal morphology and blood perfusion, missing the full spectrum of molecular information. Raman spectroscopy addresses this gap while keeping the investigation non-invasive and label-free. Although previous studies have demonstrated the huge diagnostic potential of combining both modalities for in vivo biological tissue measurement, some have either employed unsafe optical power levels for in vivo retinal measurements or presented results that were negative or contradictory. In this study, we have developed an eye-safe multimodal in vivo label-free imaging system and demonstrate the potential of this device by investigating the retina of a living albino rat. The acquired Raman spectra showed relevant Raman bands in comparison with the previous ex vivo studies. Using this multimodal imaging system for non-invasive retina measurements of transgenic rodents holds the potential to advance the understanding of the pathophysiology of both ophthalmic and neurodegenerative diseases.
    University Bibliography Jena:
    fsu_mods_00019976External link
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